Injection Lipolysis

History, Product and Procedure

Injection Lipolysis / Lipodissolve was created for the removal of small fatty deposits over various regions of the body. This treatment is not directly a method of weight loss, rather a treatment for body sculpting or contouring. Injection Lipolysis treatment is meant to act as an adjunct to healthy eating habits and regular exercise, not in replace of it. Patients are encouraged to undergo positive lifestyle change to improve the outcomes and longevity of the treatments. Lipolysis injections have been developed to eliminate small localised fat deposits or to moderately reduce fat and also benign lipomas with patients who do not want to undergo a surgical intervention for whatever reasons.

Injection Lipolysis therapy began in 1995 in by Dr Rittes from Brazil who began treating patients with a well established liquid lecithin product; phosphatidylcoline, a chemical produced from the Soya bean that has been used therapeutically for over 15 years, originally for intravenous treatment of cholesterol level disorders and more recently for injections into fat deposits under the skin.

PPC is directly injected into the fat deposits to be treated. As a rule, anesthesia is not necessary. Overdoses or intoxications have not become known up to date. The intervals between treatments depend upon the individual dispositions and the body regions and may amount to 6-8 weeks. Again depending upon the body region, the number of treatments may amount to 2-4 sessions.

Leading up to 2004 – over 8,500 patients were treated without any observed long term side effects. When processesing soy beans to soybean oil, soyalecithin arises as a by-product; the soyalecithin is a phosphatidylcholine with the same molecular structure as human phosphatidylcholine. This product is approved and registered in approximately 54 countries.

The benefits of Injection Lipolysis therapy, as compared with other methods of body contouring are:

  • It is a non-invasive procedure – the treatments take between 15 – 45 minutes
  • Patients can return to their daily duties after the treatment, without the need for any kind of special clothing or apparatus. It is less prohibitive regarding cost and the need for surgery.

Treatment areas:

New areas are being added:

  • Cheeks
  • Double Chin
  • Jowls
  • Axillary fold
  • Iliac Crest
  • Love Handles
  • Gluteal Banana
  • Buttocks
  • Saddle Bags
  • Inner and Outer Thighs
  • Under and Upper Belly
  • Upper arm
  • Knee


There are limited contra-indications for this therapy; however those who should not be treated with Injection Lipolysis are pregnant or nursing mothers, children and diabetics or those with vascular disease microangiopathies.

Those with ‘adverse’ indications are patients with auto-immune problems, serious liver disease, acute infections and chronic risk infections, serious adiposity, known hypersensitivity against one of the known products (i.e. soybean), serious renal disease, allergies, coagulation defects or menses defects.
Additional side effects that can be expected are swelling and excessive warmth of the injection spot, haematoma, sensitivity to pressure and pain in the treated area. As with most procedures, not all side effects occur for all patients, and those that do occur will be of varying duration.

Statistics and Benefits

The Lipolysis Report 2004 has based its findings on results collated from 470 patients treated in 1061 treatment sessions. There is also over 350 physicians in 21 countries who are currently collecting additional data on 5000 patients who have completed Injection Lipolysis treatment.

Patient satisfaction is detailed in the 2004 Lipolysis report and it must be noted that unlike surgical procedures, Lipolysis does not produce any immediate effect, but only after 2-3 treatments over a period of up to 6 months. Many patients have in fact confirmed that they find this slower rate of change as positive because they are not confronted with the psychological effects of an abrupt change in their physical appearance.

It was recorded that in 93% of all cases, whereby with growing experience of the treating physicians, the non-responder rate decreases still further.